Endocrine Abstracts

Introduction: Pheochromocytomas and paragangliomas(PPGLs) are catecholamine-secreting tumors. Catecholamine excess contributes to bone resorption and secondary osteoporosis. PPGLs are treated surgically but limited data exists on the subsequent effect on bone status.Aim: To evaluate bone metabolism(BM) and bone mass density(BMD) before and after successful surgery of PPGLs.Methods: A retrospective study on (BM) of (PPGLs) patients ...

Introduction: Ganglioneuromas (GNs) are rare, benign tumors, arising from neural crest cells. Their incidence amongst adrenal masses is 0.3%-6%. The majority are incidentalomas and hormonally inactive but a subset may cause compressive effects. Presentation in the context of genetic syndromes (NF1/NF2, RET, MAX, Von Hippel Lindau disease) has been reported. We present two cases of adrenal GNs: Case 1. A 31-year-old female patient who presented with a history o...

Background: In patients with adrenal nodules increased 17-OH Progesterone (17-OHP) does not necessarily indicate congenital adrenal hyperplasia (CAH) since adrenocortical tumors may harbor defects in steroidogenesis resulting in high steroid precursors, either basally or, usually, after Synacthen stimulation. Secretion of precursors has been associated with malignancy but it can also be present in benign adenomas.Case Presentation: A 62-year-old lady wit...